Curing Atrial Fibrillation: A Comparison of 2 Keyhole Techniques

Minimal versus Maximal Radiofrequency Ablation to Achieve Enduring freedom from Atrial Fibrillation

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000863033

Acronym

MINIMAX Study

Enrollment

150

Registered

2010-10-14

Start date

2010-05-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Atrial fibrillation is a common heart rhythm disorder and is associated with heart rhythm irregularity. This trial aims to compare the relative efficacy of 2 different keyhole procedures to cure atrial fibrillation.

Interventions

Pulmonary vein isolation by wide encircling ablation of ipsilateral veins with linear ablation of the intervenous ridge. This procedure takes 2-4 hours and involves advancing specialized catheters into the heart via a keyhole approach, and using heat energy to place strategically-positioned scars in the upper chambers of the heart to cure atrial fibrillation. It is done as a one-off procedure, though occassionally a second procedure is required.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

Age 18 or greater Paroxysmal atrial fibrillation Failure of at least one antiarrhythmic medication Suitable for 1st time atrial fibrillation ablation

Exclusion criteria

Pregnancy Contraindications to atrial fibrillation ablation

Outcome results