A pilot study to investigate the impact of Respiratory Gated Positron Emission Tomography (PET) scanning on classification and diagnostic accuracy in patients with Solitary Pulmonary nodules

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000790044

Enrollment

Registered

2010-09-23

Start date

2011-11-28

Completion date

2012-08-10

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a pilot study to investigate a new scanning technique called respiratory gated (4D) PET scanning in patients with solitary pulmonary nodules. Who is it for? You can be part of this trial is you have a single round lesion in your lung that needs investigation with a PET scan. Trial details The participants will recieve their whole body PET scan as per normal but they will have an additional 4D PET scan that will take an extra 10 minutes. The 4D PET scan is a scan that will create a movie of the lung breathing. This movie can reduce blurring of lesions caused by movement due to normal breathing. The study aims to see the proportion of patients who have a change in the way the cancer is classified as a result of the additional 4D PET scan

Interventions

A patient with a SPN will receive a Respiratory Gated (4D) PET scan as well as their whole body PET scan. The participant will have a 20minute whole body Positron Emission Tomography/Computerised Tomography (PET/CT) scan as per normal. Immediatly after the whole body scan the patient will have a 10minute 4D scan. The total scan time is approximatly 30 minutes. The participant will have to remain still for both scans and try to breath in a regular pattern. The only difference between the tw

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Diagnosis

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Evidence of a solitary pulmonary nodule with no histopathology for evaluation with Fluorodeoxyglucose (FDG) PET/CT scanning.

Exclusion criteria

Breathing trace technically unsatisfactory for respiratory gating

Outcome results