Improving the diagnosis of liver cancer with Positron Emission Tomography (PET) scanners by applying mathematical models and using breathing motion correction methods

Use of kinetic analysis and respiratory gating of Positron Emission Tomography (PET) scans to increase the sensitivity for detection of liver metastases in colon cancer prior to attempted curative surgery.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000747022

Enrollment

Registered

2010-09-07

Start date

2011-01-01

Completion date

2014-06-01

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study is aimed at improved PET scanning diagnosis of liver secondaries from colon cancer. There will be no recruitment of patients from outside of the Royal Brisbane and Women's Hospital.

Interventions

PET scanning, kinetic analysis, respiratory motion correction. This involves 60 additional minutes of PET scanning (after the routine PET tracer injection up until the usual time of commencement of the routine PET scan at 60 minutes post injection). The information for kinetic analysis and respiratory motion correction are obtained during this 60 minute scan.

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Diagnosis

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Previous colon cancer, known or suspected colon cancer metastases in the liver, referred for routine PET scan as part of their clinical workup, able to lie in PET scanner for additional 60 minutes

Exclusion criteria

Unable to undergo PET scanning

Outcome results