Skip to content

How useful is spirometry during and following exacerbations of chronic obstructive pulmonary disease?

For patients admitted for a suspected exacerbation of chronic obstructive pulmonary disease (COPD), does use of spirometry compared with no spirometry influence diagnosis and management, and is it predictive of outcomes?

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12610000745044
Enrollment
48
Registered
2010-09-07
Start date
2010-09-07
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A simple breathing test, called spirometry, provides valuable information in the diagnosis and assessment of many lung diseases, including chronic obstructive pulmonary disease (COPD). There is little knowledge regarding usefulness of this test during COPD exacerbations requiring hospitalisations, and so is rarely performed. The purpose of this study is to assess how useful it is to perform spirometry in this setting.

Interventions

Spirometry- once consented, the researcher will approach the patient at the bedside to perform spirometry with a hand-held portable spirometer and measure the usual values of forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), forced expiratory ratio (FER), inspiratory capacity (IC) etc. This will first occur within 24 hours of admission and then daily until discharge, and again at a 4 week follow-up. Testing should take around 30mins each time.

Sponsors

GlaxoSmithKline (GSK)
Lead SponsorCommercial sector/Industry

Study design

Allocation
Randomised controlled trial
Primary purpose
Diagnosis

Eligibility

Sex/Gender
All
Age
50 Years to No maximum
Healthy volunteers
No

Inclusion criteria

current/ex smokers - 10 year pack history hospital admission diagnosis of COPD exacerbation

Exclusion criteria

Non-english speaking Confused/comatose/unable to follow instructions Requiring mechanical ventilation/intensive care

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026