None listed
Conditions
Brief summary
The purpose of this study is to know if it is feasible to do a randomized controlled trial by allocating the freshest available red blood cells in critically patients, versus standard care.
Interventions
Transfusion of freshest available red blood cells. The freshest red blood cell is defined by the shortest number of days between the collection of the blood and its delivery.
The freshest available red blood cells will be take in the back of the fridge of the blood bank
The patients receiving the freshest red blood cells will be allocated in this group after randomisation
This allocation remains throughout the stay in intensive care or for the study period (6weeks)
The methods used in transfus
Transfusion of freshest available red blood cells. The freshest red blood cell is defined by the shortest number of days between the collection of the blood and its delivery. The freshest available red blood cells will be take in the back of the fridge of the blood bank The patients receiving the freshest red blood cells will be allocated in this group after randomisation This allocation remains throughout the stay in intensive care or for the study period (6weeks) The methods used in transfusion, the amoount of blood transfused depend on the needs of the patients and on the doctor's prescription. These characteristics are not defined by the protocole.
Sponsors
Monash University
Study design
Allocation
Randomised controlled trial
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients hospitalised in the intensive care unit Age equal or higher than 18 years Require administration of at least one red blood cells unit
Exclusion criteria
Palliative care Transplant Oncology and Haematology patients Patients with known red blood cells antibodies requiring antigen negative units (Patients will be withdrawn from the study if the requirement for antigen-specific red cells is identified after randomisation)
Outcome results
None listed