Ciclosporine Azathioprine versus Tacrolimus mycophenolate mofetil in renal transplantation

A randomized prospective open trial comparing cyclosporine/azathioprine versus tacrolimus/mycophenolate mofetil , associated to rabbit anti-thymocyte globulines (rATG) induction and prednisone in kidney transplantation

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000697088

Acronym

CATM2

Enrollment

300

Registered

2010-08-24

Start date

2000-02-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Randomized and open monocentral trial evaluating 2 immunosupressive regiments in prevention of acute rejection in renal transplantation.

Interventions

Tacrolimus 0.075 mg/Kg/twice daily oral tablet & mycophenolate mofetil 1000 mg/twice daily oral tablet. The duration of the two treatments is prolonged during all the graft survival duration.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Educational / counselling / training

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

patient with chronic renal failure indicating a renal transplantation

Exclusion criteria

recipient hepatitis B surface antigen positive older 65 years

Outcome results