None listed
Conditions
Brief summary
This study will investigate the mood, cognitive and performance impairments in obstructive sleep apnoea patients and shift workers compared to a control group. A series of questionnaires and tasks that measure driving ability, attention, reaction time, and higher thinking functions will be undertaken. The study hopes to determine whether different patterns of neuropsychological function and sleepiness predict simulated driving performance and accident risk.
Interventions
One afternoon of testing involving 1) neuropsychological assessments: Logical Memory, Trails A & B, Digit Span, Stroop; 2) mood evaluation: Beck Depression Inventory, Profile of Mood States, State-Trait Anxiety Inventory; 3) driving simulation task; and 4) reaction time and sustained attention tasks: Psychomotor Vigilance Task (PVT), Oxford Sleep Resistance task (Osler-2). Testing will last for approximately four hours, commencing at 13:00.
The order of testing will be the same for every partic
One afternoon of testing involving 1) neuropsychological assessments: Logical Memory, Trails A & B, Digit Span, Stroop; 2) mood evaluation: Beck Depression Inventory, Profile of Mood States, State-Trait Anxiety Inventory; 3) driving simulation task; and 4) reaction time and sustained attention tasks: Psychomotor Vigilance Task (PVT), Oxford Sleep Resistance task (Osler-2). Testing will last for approximately four hours, commencing at 13:00. The order of testing will be the same for every participant: Logical Memory, Trails A & B, Digit Span, Stroop, Beck Depression Inventory, Profile of Mood States, State-Trait Anxiety Inventory, Logical Memory Recall, first Osler-2, driving simulation, PVT, second Osler-2
Sponsors
Institute for Breathing and Sleep
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
1) Current driver licence for all participants 2) Obstructive sleep apnoea participants: moderate to severe obstructive sleep apnoea (apnoea hypopnoea index > 20/hr and Epworth Sleepiness Scale score >8). 3) Shiftwork participants: at least 3 months of rotating shifts
Exclusion criteria
1) Chronic neurological illness or significant medical co-morbidity 2) Chronic psychiatric illness 3) Visual acuity problems not correctable with glasses 4) Regular use of sedating medication 5) Inability to give informed consent 6) Inability to speak or write English. Shiftworker participants only: a Multivariable Apnoea Prediction Score (>0.5). Control participants only: a Multivariable Apnoea Prediction Score (>0.5) and/or Epworth Sleepiness Scale score (>10).
Outcome results
None listed