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A pilot, parallel-group, randomised controlled trial on the effectiveness of 10% Formalin in the treatment of plantar warts.

A randomised controlled pilot study on the effectiveness of 10% Formalin in the treatment of plantar warts.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12610000679088
Enrollment
32
Registered
2010-08-18
Start date
2010-08-30
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary purpose of this study is to investigate how effective 10% Formalin is as a topical treatment for eradicating plantar warts. Our hypothesis is that 10% formalin will be more effective in curing plantar warts then the control over a maximum of 6 months.

Interventions

The intervention will involve an initial appointment where the participant will be randomised to either of the treatments (10% formalin or the placebo) and screened for eligibility. The participants will then have the area of their plantar wart debrided (this is where the dead skin overlying the wart will be scraped away) the primary investigator will apply the 10% Formalin treatment solution topically over the wart using a cotton bud, which has been dipped into the solution (this will occur at

The intervention will involve an initial appointment where the participant will be randomised to either of the treatments (10% formalin or the placebo) and screened for eligibility. The participants will then have the area of their plantar wart debrided (this is where the dead skin overlying the wart will be scraped away) the primary investigator will apply the 10% Formalin treatment solution topically over the wart using a cotton bud, which has been dipped into the solution (this will occur at monthly appointments to a maximum of six months).The participant will then be given instructions (both written and verbal) where they will sand the wart area with 120 grit sand paper and topically apply the 10% Formalin treating solution to the wart. The participant will do this every night for a month (maximum treatment period of 6 months). At any of the monthly appointments if the participant is deemed to no longer have the plantar wart i.e. it has been cured, the participant will cease to use the treatment and they will attend a final follow-up appoinment where they will be clinically examined to assess reoccurance of the plantar wart. The initial appoinment is estimated to take between 30-45 minutes. Thereafter the monthly appoinments are estimated to take between 15-30 minutes and the final follow-up appointment would take about 15 minutes.

Sponsors

Rolf Scharfbillig
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
4 Years to No maximum
Healthy volunteers
No

Inclusion criteria

plantar wart present on at least one foot, multiple warts will be treated as one person not one wart, willingness to participate in the study, ability to communicate in english

Exclusion criteria

sensitivity to formalin, younger than four years of age, immunocompromised, vascular or neurologically compromised in feet

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026