None listed
Conditions
Brief summary
The main focus of this study is to look at the effect of prematurity on kidney growth and function . Kidney size and function in a cohort premature babies (< 32 weeks) is compared with control group (term babies).The study also looks at the rate of kidney growth when a baby is born premature .It will also determine if retinal vasculature ( arterial/venous diameter and branching angles) has correlation to kidney size , kidney function , baby's sex and ethnicity. Most literature says that the foetal retinal matures by 36 to 37 weeks gestation . Baby with significant Retiopathy of prematurity (ROP) will be excluded from analysis .
Interventions
Premature babies will undergo ultrasound kidneys, eye examination ,blood test for renal function and urine analysis twice ( at 32 weeks corrected age and a at 38 weeks corrected age). The investigations will take approximately 1 hour on each occasion. The total duration of the study is for 24 months
Sponsors
Dr Yogavijayan Kandasamy
Eligibility
Sex/Gender
All
Age
0 to 42 Weeks
Healthy volunteers
No
Inclusion criteria
Premature babies less than 32 weeks of gestation with parental consent would be recruited into this study.
Exclusion criteria
Babies with congenital renal, eye and chromosomal abnormalities will be excluded from this study.
Outcome results
None listed