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The role of long chain omega-3 polyunsaturated fatty acids (fish oil) on weight management

Does supplementation with long chain omega-3 polyunsaturated fatty acids assist with weight management in obese individuals

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12610000659000
Acronym
nil
Enrollment
50
Registered
2010-08-12
Start date
2007-02-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Weight gain has been associated with increased inflammation and fish oil supplementation has been shown to possess anti-inflammatory properties. This study is investigating whether fish oil supplementation will reduce inflammation and assist weight loss and weight loss maintenance

Interventions

A low kilojoule (kJ) diet of 5,000 to 6,000 kJ/day, based on the Australian Guide to Healthy Eating, will be followed for 12 weeks. Participants will also consume, by mouth, 6 x 1g/day fish oil capsules composed of 270mg Docosahexaenoic Acid (DHA) and 70mg Eicosapentaenoic Acid (EPA) per capsule. Participants then progress to weight maintenance for 10 weeks and continue to take the 6 x 1 g/day fish oil capsules. Participants receive 1 x 30 minutes per week education sessions on dietary modifi

A low kilojoule (kJ) diet of 5,000 to 6,000 kJ/day, based on the Australian Guide to Healthy Eating, will be followed for 12 weeks. Participants will also consume, by mouth, 6 x 1g/day fish oil capsules composed of 270mg Docosahexaenoic Acid (DHA) and 70mg Eicosapentaenoic Acid (EPA) per capsule. Participants then progress to weight maintenance for 10 weeks and continue to take the 6 x 1 g/day fish oil capsules. Participants receive 1 x 30 minutes per week education sessions on dietary modification and behaviour change for the first four weeks of weight loss

Sponsors

The University of Newcastle
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

Body Mass Index (BMI) between 30 and 40. Can consume fish. Can swallow capsules

Exclusion criteria

BMI >40; Diabetic; Already consuming fish oil capsules or 2 or more oily fish meals/week; Has an inflammatory condition

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026