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Accumulative Benefit of Light Exercise breaks for reducing diabetes risk

The cumulative effects of repeated bouts of prolonged sitting with and without intermittent short-term physical activity on postprandial glucose and lipid metabolism, in overweight middle-aged adults.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12610000657022
Acronym
ABLE (Accumulative Benefit of Light Exercise) breaks study
Enrollment
24
Registered
2010-08-11
Start date
2010-11-08
Completion date
2012-06-07
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

There is emerging evidence that people who break up their sitting time with activity breaks (such as light walking) may have better blood glucose and blood fat levels than people who sit for prolonged periods without activity breaks. This study aims to test the cumulative effects of three consecutive seven hour days of prolonged sitting on blood glucose and blood fat levels with and without intermittent breaks of light-intensity activity.

Interventions

This randomised crossover trial involves three consecutive days (total duration=21 hours) of prolonged sitting with intermittent light-intensity activity breaks. Participants will remain seated for the initial 80mins (steady-state) period, after which they will complete a 2 min bout of light-intensity walking activity on a treadmill (level, firm surface, slow pace - 3.2km/hr). Participants will then return to the seated position. The light-intensity walking breaks will be repeated on another 16

This randomised crossover trial involves three consecutive days (total duration=21 hours) of prolonged sitting with intermittent light-intensity activity breaks. Participants will remain seated for the initial 80mins (steady-state) period, after which they will complete a 2 min bout of light-intensity walking activity on a treadmill (level, firm surface, slow pace - 3.2km/hr). Participants will then return to the seated position. The light-intensity walking breaks will be repeated on another 16 occasions every 20 mins during a 7 hour period (total walking time=34mins). There is a 7 day 'wash-out' period between the intervention and comparator condition.

Sponsors

Baker IDI Heart and Diabetes Institute
Lead SponsorCharities/Societies/Foundations

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

Inclusion criteria includes: overweight or obesity (body mass index (BMI) greater than or equal to 25 kg/m2 but less than or equal to 45 kg/m2).

Exclusion criteria

Exclusion is based on: pregnancy; employment in a non-sedentary occupation (< 5 hours total sitting during the typical workday); currently watching < 2 hours of total screen (including television, computer or electronic games) time per day; use of carbohydrate or lipid-lowering medication; greater than or equal to 5 previous vasovagal syncope episodes or epilepsy; known physical activity contraindications; major illness/injury (acute or chronic), smokers; or physical or medical problems that may limit the ability to perform the necessary light-intensity walking, and the use of aspirin or other anticoagulants.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026