None listed
Conditions
Brief summary
Craniosynostosis leads to pathological shapes of the skull. The standardized bilateral frontoorbital advancement (FOA) corrects the shape of the skull and the intracranial volume is actively increased. The extent of the intracranial volume obtained by the operation is unknown so far. The optimal extent cannot yet be predicted and has to be empirically determined by the surgeon. The purpose of this prospective examination is to determine the volume increase by 3D magnetic resonance imaging (3D-MRI) of the children operated on by means of FOA. Using the technique of segmentation, the intracranial volume of 54 children with various forms of craniosynostosis should be measured on pre- and postoperative 3D-MRI scans. For comparisons the intracranial volume (ICV) measurements should be obtained just prior to surgery and 7 days postoperatively in the same way. The accuracy of the indirect measuring method should be validated by means of additional direct volume measurements of five dry skulls.
Interventions
Standardized Frontoorbital Advancement according to Muehling in Patients with Craniosynostosis:
Description of Surgery: Advancement of the Frontoorbital Bone Segment
Duration of Oberservational Study: 5 years
The approximate duration of the procedure varies and lies in the nature of a surgical procedure
Sponsors
Heidelberg University Hospital
Eligibility
Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No
Inclusion criteria
- Craniosynostosis - Frontoorbital Advancement - Pre-operative and Post-operative Magnetic Resonance Imaging (MRI)
Exclusion criteria
- no frontoorbital advancement planned
Outcome results
None listed