None listed
Conditions
Brief summary
Continent catheterizable ileal pouches must be regularly rinsed to reduce the risk of urinary tract infections (UTI). The aim of this study is to compare the standard method of "aseptic ISC and rinsing with NaCl 0.9% solution" to "hygienic ISC and rinsing with tap water" to assess whether UTI rate, quality of life (QoL), and costs differ. The hypothesis is a lower UTI rate, better QoL and lower costs with the method with tap water.
Interventions
Patients with continent catheterizable ileal pouch are prospectively randomized in a two-arm crossover study. One study arm is "aseptic intermittent self catheterisation (ISC) and rinsing with sodium bicarbonate (NaCl) 0.9% solution". This study arm lasts 90 days. Every morning a dipstick urine test is done by the patient to check nitrite in urine. After that, the umbilicus is cleaned with aseptic solution. Then the pouch is catheterized with a sterile single-use catheter. After catheterizing, the poch is rinced with 3 times 60 milliliters of sterile NaCl 0.9% solution. In case of nitrite-negativity, the same procedure is repeated next morning. In case of nitrite-positivity, the same procedure is repeated at the next catheterization 4 hours later. The entire procedure takes about 15 minutes. In monthly intervals urine cultures are collected. In case of symptomatic urinary tract infection (UTI) an antibiotic therapy is prescribed. Evaluation of quality of life and costs by questionnaire. There is washout period is one day between the two study arms of the cross-over study.
Sponsors
Study design
Eligibility
Inclusion criteria
Continent catheterizable ileal pouch since 2 weeks or more
Exclusion criteria
Chronical urinary tract infection