Physical activity levels of patients with cystic fibrosis admitted to hospital with an acute pulmonary exacerbation

The effect of hospitalisation with an acute pulmonary exacerbation on the physical activity levels, exercise tolerance and grip strength of patients with cystic fibrosis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12610000595011

Enrollment

Registered

2010-07-23

Start date

2010-10-26

Completion date

2011-10-25

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To determine objectively how inactive cystic fibrosis patients are during and after a hospital admission for an acute pulmonary exacerbation by assessing them using a highly accurate physical activity level monitor. The study also seeks to determine whether exercise tolerance and skeletal muscle strength are reduced during periods of hospitalisation for an acute exacerbation.

Interventions

Physical activity levels will be measured, using a SenseWear Pro 3 Armband, for a 24 hour period between days 3 and 5 of the hospitalisation period and 1 month after discharge. A clinical exercise test, the modified shuttle walk test, will be undertaken on day 5/6 of hospitalisation and 1 month after discharge from hospital to assess exercise tolerance. The exercise tests will be undertaken at (slightly) different time points to the assessment of physical activity levels to avoid the exercise tests affecting the measurement of physical activity levels. Skeletal muscle grip strength will be measured between days 3 and 5 of the hospitalisation period and 1 month after discharge using a calibrated Jamar dynamometer. The study will continue until the required sample size (n = 34) is achieved.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Adult patients with cystic fibrosis admitted to the Royal Adelaide Hospital with an acute exacerbation of their pulmonary disease.

Exclusion criteria

Patients will be excluded if they are unwilling to participate or unable to commit to the 1 month follow-up measurements.

Outcome results