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Exercise and Cognitive Behavioural Therapy for Knee Osteoarthritis

Addressing pain in knee osteoarthritis: physiotherapist-delivered exercise and cognitive behavioural therapy.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12610000533099
Enrollment
222
Registered
2010-07-01
Start date
2010-08-16
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this study is to investigate the benefits of a 12-week intervention involving 10 weekly treatment sessions delivered by a physiotherapist on a one-to-one basis. The study will examine the effectiveness of a combined exercise and Cognitive Behavioural Therapy (CBT) intervention compared to each intervention (CBT or Exercise) alone. Hypothesis: A 12-week intervention that combines exercise with CBT will be more effective in improving pain (visual analogue scale) and physical function (WOMAC subscale) than either a 12-week intervention of exercise alone or CBT alone in individuals with painful radiographic knee OA.

Interventions

To investigate the benefits of a 12-week intervention involving 10 weekly treatment sessions delivered by a physiotherapist on a one-to-one basis. This is a 12 week intervention because prior to meeting the physiotherapist at week 1 and week 12 the participant will attend the university for laboratory assesssment and we will request that the participant wear a pedometer for 7 days straight and record the number of steps they have taken on a data collection sheet during both periods. They will se

To investigate the benefits of a 12-week intervention involving 10 weekly treatment sessions delivered by a physiotherapist on a one-to-one basis. This is a 12 week intervention because prior to meeting the physiotherapist at week 1 and week 12 the participant will attend the university for laboratory assesssment and we will request that the participant wear a pedometer for 7 days straight and record the number of steps they have taken on a data collection sheet during both periods. They will see the physiotherapist from weeks 2-11. The study will examine the effectiveness of a combined exercise and Cognitive Behavioural Therapy (CBT) intervention compared to each intervention (CBT or Exercise) alone. All interventions will be delivered by a sole health care professional - specially trained physiotherapists. This means that the exercise and CBT components can be integrated and delivered in the same session. Intervention Groups: i) Exercise Alone - 25 minute treatment sessions X 10 sessions This component is comprised of: -quadraceps strengthening -sitting knee extension -hip abductor strengthening -partial wall squats -sit to stand exercise -hamstring strengthening -step up and step down exercise ii) CBT Alone - 45 minute treatment sessions X 10 sessions This component is comprised of: -explanation of the gate control theory -progressive muscle relaxation -relaxation training and and explanation of its benefits -identifying and challenging negative thoughts -problem solving -pleasant imagery and counting backwards iii) CBT plus Exercise - 70 minute treatment sessions X 10 sessions This component is comprised of a combination of i) & ii) above.

Sponsors

The University of Melbourne, School of Physiotherapy
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
50 Years to No maximum
Healthy volunteers
No

Inclusion criteria

-All participants will have knee joint osteoarthritis (OA) in at least one knee fulfilling the American College of Rheumatology classification criteria - Over 50 years of age - Pain on most days of the past month a - Self-reported level of average pain in the past week of greater than or equal to 4 out of 10 on a numeric rating scale - Greater than or equal to 25 on the WOMAC physical function scale

Exclusion criteria

-History of lower limb joint replacement -Surgical waiting list for knee or hip replacement; knee surgery, intra-articular steroid or Synvisc (registered trademark) injection planned or within the past 6 months -Systemic arthritic condition such as rheumatoid arthritis; received (within 6 months) -Currently receiving any physiotherapy for knee OA; participation in a formal lower limb exercise program within the past 6 months or planning to commence exercise or other treatment for knee OA in the next 12 months -Currently walking >15 minutes continuously more than 2 times per week -Unable to walk without a gait aid -Self-reported medical condition precluding safe exercise participation (excessive shortness of breath or any underlying condition) -Previous CBT/pain coping skills training.

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 25, 2026