A randomized trial comparing Transurethral resection of the prostate (TURP) with 120W photoselective vapourization of the prostate (PVP) in men with lower urinary tract symptoms

Laser vapourization of the prostate in men with benign prostate enlargement. Long term results and cost analysis.

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000518066

Enrollment

150

Registered

2010-06-23

Start date

2010-09-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

PVP is a new procedure that may one day be able to replace TURP as the main treatment for men with benign prostate enlargement. There has only ever been one randomized controlled trial of PVP with TURP and this was using the now outdated 80W model. Recent advice from the UK National Institute for Health and Clinical Excellence has stated that PVP should only be used in the context of randomized controlled trials. We intend to assess whether the procedure has long term benefits for patients and whether it is cost efective for health providers.

Interventions

Laser vapourization of prostate (PVP) compared to TURP. PVP uses a 120W green light laser to vapourize prostate tissue to create an opening to allow an improved urinary flow. The procedure takes between 30 and 80 minutes. There is very little bleeding and saline can be used to washout the bladder.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

Male

Age

50 Years to 85 Years

Healthy volunteers

Inclusion criteria

Urinary flow rate < 15mls/sec, IPSS > 12

Exclusion criteria

Prostate cancer, inability to provide informed consent

Outcome results