Randomised Controlled Trial of Cognitive Behavioural Therapy for the Treatment of Anxiety and Depression in Parkinson’s Disease

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000455066

Enrollment

126

Registered

2010-06-03

Start date

2010-08-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study examines the effectiveness of a group Cognitive Behavioural Therapy (CBT) treatment designed to help people with Parkinson's Disease manage anxiety and depression problems.

Interventions

Cognitive Behavioural Therapy (CBT) adapted specifically for people with Parkinson's Disease experiencing anxiety and depression. Topics covered in therapy include relaxation techniques, cognitive modification (eg, automatic thoughts, recognising unhelpful thinking styles), behavioural modification and active coping. The treatment will be run in a group format of 6-8 participants and facilitated by two therapists. Treatment comprises 8 weekly sessions, each of 2-hour duration.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1) At least 6-months post-diagnosis of Parkinson’s Disease 2) Stable use of antiparkinsonism medications 3) Meet the criteria for depression and/or any anxiety disorder as outlined in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders Version 4; Text-Revision (DSM-IV-TR) 4) If on antidepressant medication, this must have been stabilised (same medication and dosage) for at least 3 months prior to baseline assessment 5) If on antidepressant medication, agreement to remain on the same medication and dosage over the duration of the study where possible 6) Agreement to not pursue other psychological treatments during the course of the study and over the 6-month follow-up period.

Exclusion criteria

1) Undergoing concurrent psychological treatment 2) Individuals who exhibit cognitive impairment (defined as a Mini Mental State Examination score < 24) 3) Meet DSM-IV-TR criteria for Psychosis 4) Show high suicide risk (defined as meeting the diagnosis for Current Suicidality as assessed by the Mini Neuropsychiatric Interview; MINI)

Outcome results