Use of bifocal scanning (Vivascope, trademark [TM]) versus tissue biopsy in diagnosis of skin cancers

Assessment of Reflectance Confocal Microscopy in the Diagnosis of Non-Melanoma Skin Cancer and Benign Lesions Versus Normal Skin: Observer-Blinded Evaluation by Surgeons and Pathologists

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12610000450011

Enrollment

100

Registered

2010-06-02

Start date

2009-04-16

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Purpose of the study is to determine the place, if any, of bifocal tissue scanning in diagnosis of skin cancers as compared to tissue biopsy. We hope to determine if a) there is a better and easier way of diagnosis of skin lesion other than biopsy and b) if there is a reliable method of determining the limits of spread of the skin lesion to reduce the need for repeated surgeries.

Interventions

Use of Confocal reflectance Microscopy in diagnosis of Non-melanoma skin cancers as compared to histological diagnosis 1-Confocal micrscopy involves a 10 to 25 minute session, where an adherent probe is placed over the lesion of interest. The operator of the microscope then proceeds to generate images of the lesion. This can take anything from 10 to 25 minutes, depending on the size of the lesion. At the end of the session the probe is removed. No sensation other than slight pressure from the we

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

All patients referred to Plastic and Reconstructive Surgery Department of Royal Adelaide Hospital or The Queen Elizabeth Hospital for excision, excisional biopsy, or biopsy of non-melanoma skin lesion who are willing to participate in the study

Exclusion criteria

Patients not willing to participate in the study, patients not able to understand the study information, patients under the age of 18

Outcome results