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Short-term efficacy of neural mobilisation for patients with nerve-related neck and arm pain

Short-term efficacy of standardised neural mobilisation for patients with nerve-related neck and unilateral arm pain

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12610000446066
Enrollment
84
Registered
2010-06-01
Start date
2009-07-21
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Some patients with neck and arm pain have symptoms because nerves in the neck and arm have become overly sensitive to movement. There is some evidence that this type of neck and arm pain can be well managed with specific treatment to the nerves in the neck and arm (nerve mobilisation). However, the evidence is limited and we cannot predict which patients respond best to nerve mobilisation. The primary aim of this trial is to determine whether nerve mobilisation leads to clinically important improvements in pain and function for patients with nerve-related neck and arm pain. The secondary aim is to determine if a set of clinical findings can accurately predict which patients with nerve-related neck and arm pain will respond best to nerve mobilisation.

Interventions

Participants assigned to neural mobilisation will receive one-on-one treatments with a physiotherapist (4 treatments over 2 weeks). The physiotherapist will apply 2 manual therapy techniques and prescribe 2 nerve gliding exercises for a home program at each treatment session. The manual therapy techniques include a cervical lateral glide away from the symptomatic arm and a shoulder girdle oscillation technique. Each manual therapy technique will be applied for a total of 4 minutes at each treatm

Participants assigned to neural mobilisation will receive one-on-one treatments with a physiotherapist (4 treatments over 2 weeks). The physiotherapist will apply 2 manual therapy techniques and prescribe 2 nerve gliding exercises for a home program at each treatment session. The manual therapy techniques include a cervical lateral glide away from the symptomatic arm and a shoulder girdle oscillation technique. Each manual therapy technique will be applied for a total of 4 minutes at each treatment session. The nerve gliding exercises for the home program include a 'sliding' technique and a 'tensioning' technique biased toward the median nerve and cervical nerve roots. In a 'sliding' technique, a movement that lengthens the median nerve bed (e.g., elbow and wrist extension) is counterbalanced by another movement that shortens the nerve bed (e.g., neck side-bending toward the symptomatic arm). A 'tensioning' technique involves simultaneous movements that lengthen the median nerve bed (e.g., elbow and wrist extension combined with neck side-bending away from the symptomatic arm). Participants will perform 10-15 repetitions of the 'sliding' and 'tensioning' techniques 3 times daily on days they do not attend treatment. On days that participants attend treatment, 10-15 repetitions of the 'sliding' and 'tensioning' techniques will be performed under the guidance of the physiotherapist. This will enable the physiotherapist to check that nerve gliding exercises are performed correctly and to progress exercises as necessary. All manual therapy techniques and nerve gliding exercises will not provoke participants' symptoms. The maximum sensory response allowed during each technique is a gentle stretching or pulling sensation that settles immediately upon completion of the technique.

Sponsors

Robert Nee
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

1. Neck pain that spreads into one arm below the level of the deltoid tuberosity 2. Non-traumatic onset of symptoms 3. Symptoms present for at least four weeks 4. Composite pain rating of at least 3/10 (mean of patient's ratings of the average level of neck pain and arm pain during the previous week; pain ratings will be measured with separate 0 - 10 numeric pain rating scales) 5. Symptoms reproduced by a median nerve biased neurodynamic test 6. Ability to speak and read English for self-report items measured at baseline and four weeks after baseline

Exclusion criteria

1. Bilateral arm symptoms 2. Traumatic onset of symptoms 3. Two or more abnormal neurologic findings at the same nerve root level (C5 - T1) (i.e., decreased strength, decreased deep tendon reflex, decreased sensation) 4. Evidence of central nervous system involvement 5. Medical "red flags" that suggest non-musculoskeletal pathology 6. Physiotherapy treatment for neck and arm pain in the previous six months 7. Previous surgery on the neck or upper limb

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026