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Improving lower limb function in patients with major muscular loss or denervation following resection of a sarcoma.

The effect of a 4 stage rehabilitation programme on lower limb physical function in patients with major muscular loss or denervation following resection of a sarcoma

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12610000444088
Enrollment
12
Registered
2010-06-01
Start date
2010-05-24
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study looks at how supervised exercise programs can help in rehabilitating people with a major loss of muscle or nerves following surgery for sarcoma. Who is it for? You can join this study if you are recovering from a major loss of muscles or nerves after surgery for sarcoma. Trial details Participants will take part in a 12 week supervised rehabilitation program with exercises, 3 times per week, for 1.5 hours. The opposite unaffected limb is not used in the exercise program, and is monitored for comparison. Five tools will be used to monitor the psychological and physiological wellbeing of patients. The ultimate goal is to restore function of the affected limb to 80% of the unaffected limb, The study aims to see how well exercise is tolerated, and how effective exercises are at increasing muscle strength and mobility, and also quality of life.

Interventions

Patients will be required to attend the Hollywood Functional Rehabilitation Clinic 3 times per week, for 1.5 hours. The rehabilitation intervention is for twelve weeks and will be fully supervised by an Accredited Exercise Physiologist (Miss Chrissie Mavros). The rehabilitation intervention consists of four stages, with the ultimate goal of restoring function of the affected limb to 80% of the unaffected limb, or aged matched population from published normative data. Stage 1 aims (wks 1-2): re

Patients will be required to attend the Hollywood Functional Rehabilitation Clinic 3 times per week, for 1.5 hours. The rehabilitation intervention is for twelve weeks and will be fully supervised by an Accredited Exercise Physiologist (Miss Chrissie Mavros). The rehabilitation intervention consists of four stages, with the ultimate goal of restoring function of the affected limb to 80% of the unaffected limb, or aged matched population from published normative data. Stage 1 aims (wks 1-2): restoring hip, knee and ankle range of motion (ROM); re-activating and recruiting the appropriate lower limb muscles; introducing cardiovascular exercises. Stage 2 aims (wks 3-5): strengthening the lower limb musculature; introducing core stability; further developing cardio-vascular fitness. Stage 3 aims (wks 6-8): develop lower limb muscle strength simulating functional tasks. Stage 4 aims (wks 9-12): restore and improve physical function during all activities of daily living.

Sponsors

The University Of Western Australia; School of Sports Science, Exercise and Health
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

- last cancer treatment >6months - estimated life expectancy >12months - an indication for rehabilitation - must live in Perth metropolitan area - must speak and read english competently

Exclusion criteria

- presence of severe cardiovascular disease - cognitive disturbances that may interfere with participation in the rehabilitation programme - serious psychopathology and emotional instability that may impede participation. - Formal rehabilitation in the last 3months

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026