Fish Oil in Work Stress Study

The efficacy of eicosapentaenoic acid (EPA) rich fish oil in the amelioration of chronic work stress. An understanding of the causal relationship between dietary fatty acids and psychological stress.

Status

Not yet recruiting

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000404022

Acronym

none

Enrollment

110

Registered

2010-05-19

Start date

2010-06-30

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary aim of this study is to determine the efficacy of EPA-rich fish oil in the amelioration of chronic work stress. A secondary aim is to contribute to the understanding of the causal relationship between dietary fatty acids and psychological stress. The primary hypothesis is that that EPA-rich fish oil will significantly reduce chronic work stress in comparison to a placebo over a 16 week period.

Interventions

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and from fish oil constitute the active intervention. Each capsule will contain 1000mg fish oil, comprising 600mg marine triglycerides as EPA 550mg and DHA 110mg. Four capsules per day will deliver 2.2g EPA, and 0.44g DHA. The particpants will take the medication for 16 weeks.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

Inclusions criteria Participants with scores below or equal to 17 on the PSS asking about stress levels over the past three months at baseline Participants have not taken a course of fish oil in the past three months, and consumes less than two non-fried fish meals per week on average Participants will be instructed to maintain their usual diets which will be monitored by the electronic Food Frequency Questionnaire at t=0, t=4, t= 8, t=12 and t=16 weeks

Exclusion criteria

Exclusion criteria The following criteria will used to exclude individuals from entering the study: Participants with a know seafood allergy Participants taking immunosuppressive medications Participants with an inflammatory disorder Participants with an infection Participants that have suffered a significant trauma, such as surgery, within the last 6 months Participants with unexplained weight loss Participants with any kind of malignancy Participants with any significant disease or disorder or any condition that, in the opinion of the investigators, might interfere with the study objectives.

Outcome results