Prospective evaluation of an algorithm for coronary calcium estimation

Assessment of calcium score estimation from contrast cardiac computed tomography (CT) data in patients undergoing routine CT coronary angiography

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000354088

Enrollment

120

Registered

2010-05-04

Start date

2010-04-30

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This trial is a prospective evaluation of a new method of diagnosing coronary calcium, using standard non contrast calcium score as the reference standard.

Interventions

Software quantification and algortihmic transformation of coronary calcium from a single standard contrast CT scan of duration 0.35 to 2 seconds. Both Agatston calcium score and algorithmic caclium estimation will be performed blindly after completion of the CT scan.

Study design

Allocation

Non-randomised trial

Intervention model

Parallel

Primary purpose

Diagnosis

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Consecutive 120 patients undergoing CT coronary angiography and calcium scoring from study commencement.

Exclusion criteria

Unsuitable for calcium score evaluation: Coronary stents; Previous bypass surgery Coronary occlusion detected at CT coronary angiography CT coronary angiography unsuitable for calcium estimation: greater than 600 HU in asecneding or descending aorta; Greater than 35HU standard deviation in the ascending aorta at the level of the coronary sinsus

Outcome results