Brain Effects of Acupuncture - 1 Needle acupuncture vs Laser acupuncture

1.Functional MRI (fMRI) of Needle acupuncture at LR8 at medial knee (located between the tendons of semitendinosis and semimembranosis muscles) followed by, in same session 2.Functional magentic resonance imaging (fMRI) continues while Laser acupuncture (low level -804nm, Energy delivered Total 2.56J) at the opposite side LR8 acupoint is delivered. 3.N=16, eight healthy subjects per arm, order of Note:Laser or Needle first is randomised. 4.Single session. Duration approximately 20minutes in the scanner. 5.Block design. 16 second blocks with rest and active intervention ( needle or laser) alternating blocks. Total 9 Rests and 8 actives. 6. Active laser being 20mW low level laser activation in the 16 second blocks. 7. Needle being 0.22 x 25mm silver disposable Helio acupuncture needles stimulated at 1Hz cycles to achieve the sensation of "de qi" like a dull ache.