None listed
Conditions
Brief summary
Most newly born extremely premature infants will receive help to establish breathing by the attending health professional. Face masks are standard but leak and this may lead to ineffective ventilation. Nasal tubes have been shown to improve chest wall movement in older infants and in more mature newly born infants was associated with less aggressive resuscitation. We hypothesize that nasal tubes may be gentler and hence better in stabilising the lungs of a newly born premature infant.
Interventions
Nasal tube to deliver continuous positive airway pressure (CPAP) and/or manual positive pressure inflations to newly born premature infants in the delivery room. The manual ventilating device is the Neopuff Infant Resuscitator used at standard hospital settings. Intervention is applied until patient has been stabilised and ready for transfer to the neonatal intensive care unit.
Sponsors
Royal Women's Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
24 Weeks to 29 Weeks
Healthy volunteers
No
Inclusion criteria
Premature infants born between 24 and 29 weeks gestation at a participating hospital
Exclusion criteria
Infants with known congenital anomalies; infants receiving palliative care
Outcome results
None listed