None listed
Conditions
Brief summary
Acute ureteric colic is the pain caused by the passage of kidney stones. Standard treatment is the administration of pain-relieving medications. Intravenous (IV) fluids may also help relieve pain, may cause further pain or have no effect on pain at all. There is a lack of evidence regarding the impact of IV fluids on pain relief in acute ureteric colic. This study hopes to delineate this role by randomising participants with acute ureteric colic into two groups, both of which reflect current practice. The first group will receive IV fluids at a preset rate; the second group will receive IV fluids only with medications. Pain scores via a visual-analogue scale will be taken hourly for up to four hours; these will then be compared to see if there is any clinically significant difference in the pain scores between the two groups.
Interventions
To receive 1L normal saline intravenously over 2 hours; further intravenous (IV) fluids can be given only with administration of medications. Analgesic medications given at discretion of clinician.
Sponsors
Dr Adeline Wu
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Adult patients (aged 18 or over) who present to the Emergency Depatment with symptoms of acute ureteric colic
Exclusion criteria
Patients requiring the acute administration of IV fluids for resuscitation, suspected pyelonephritis, history of congestive cardiac failure, known renal impairment/failure, patients unable to give pain scores (eg. English as a second language, dementia), allergy to non-steroidal anti-inflammatory drugs
Outcome results
None listed