None listed
Conditions
Brief summary
This study aims to examine physiological effects of foods and beverages containing grape, olive leaf and seaweed extracts in 272 overweight and obese adults. The study will be a double-blind randomised controlled trial. Participants will consume the intervention or placebo for 16 weeks, followed by six month and 12 month reviews to monitor outcomes. The study will examine physiological effects including whether the products may result in a reduction in body weight and composition, blood pressure, cholesterol, waist circumference, appetite, and inflammation. This study will contribute significantly to the current body of knowledge of the physiological effects of these compounds, as no previous human trials have been conducted. Foods and nutrients that support and enhance metabolic pathways and reduce inflammation may provide significant alternative methods for weight loss for people with chronic disease.
Interventions
Green Tea, Coffee and purple carrot drink - all with a similar combination of grape, olive leave and seaweed extracts. There is also a green tea with mango seed extract. Participants will be allocated to one intervention beverage which is to be consumed orally, three serves per day for 16 weeks). The products will be presented as dry serves for instant rehydration with near-boiling water. The dry weights of the beverage serves are: green tea 0.6g, coffee 2.4g, purple carrot drink 4g and gree
Green Tea, Coffee and purple carrot drink - all with a similar combination of grape, olive leave and seaweed extracts. There is also a green tea with mango seed extract. Participants will be allocated to one intervention beverage which is to be consumed orally, three serves per day for 16 weeks). The products will be presented as dry serves for instant rehydration with near-boiling water. The dry weights of the beverage serves are: green tea 0.6g, coffee 2.4g, purple carrot drink 4g and green tea with mango extract 4g.
Sponsors
Dr Olivia Wright
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
Body Mass Index of 25-35kg/m^2 Stable blood pressure in the "normal" (=110/70mmHg),“high-normal” (120-139/80-90mmHg) or “mildly hypertensive” (140-159/90-99mmHg) and must be on medication if the blood pressure is 140/90 159/99 mmHg. Must be otherwise healthy. Participants must be capable of giving informed consent
Exclusion criteria
Must not be pregnant or breastfeeding Participants already consuming functional beverage products (except if participants conduct four week wash-out period). Participants will be required to withdraw from the trial and seek further medical advice if there is substantial elevation in blood pressure (ie >159/99) at any time, or any sudden drop in blood pressure (<100/60).
Outcome results
None listed