The effect of an herbal supplement on memory in people who have had a mild traumatic brain injury

Enzogenol supplementation for improving cognitive function in post-traumatic brain injury (TBI) subjects: a pilot study

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000107022

Enrollment

Registered

2010-02-02

Start date

2010-01-10

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Many people who have had a traumatic brain injury experience problems in processing information that can last for many years.Our pilot clincial trial will examine if a herbal supplement can improve memory and information processing if people who experienced a head injury 6-12 months ago and are experiencing persistent cognitive difficulties. The study hypothesis will that improvements in cognitive ability will occur in participants taking the herbal supplement in comparison to the group taking the placebo.

Interventions

Pine bark extract supplement, 2x500mg taken once per day for 6 weeks by oral capsule

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Healthy volunteers

Inclusion criteria

6-12 months post mild TBI Experiencing persistent cognitive difficulties Willing to avoid taking other herbal supplements for the duration of the study

Exclusion criteria

1) Not fluent in English or have dysphasia 2) Unable to give informed consent 3) Known to have a medical condition that could impact on the results 4) Pregnancy or breastfeeding 5) Known allergy to pine trees 6) Current use of anticoagulant medication

Outcome results