Treatment of Lentigo Maligna with imiquimod 5% cream.

Treatment of Lentigo Maligna by imiquimod 5% cream as assessed by pathological assessment of the surgical excison specimen of the complete treated area

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000066088

Enrollment

Registered

2010-01-20

Start date

2006-01-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The objective of the study is to determine how effective imiquimod cream is in curing lentigo maligna and whether it is a possible replacement for surgical excison as the primary treatment.

Interventions

imiquimod 5% cream masaged directly into the lentigo maligna each day from Monday to Friday with breaks from treatment on Saturday and Sunday and any other day when the inflammation due to the cream is intolerable. This is done for 12 weeks.

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

lentigo maligna greater than 5mm diiameter

Exclusion criteria

detection of invasive melanoma

Outcome results