Reducing Acute Coronary Syndrome Time in the Emergency Department for Patients with Non-Traumatic Chest Pain

In patients presenting to an Emergency department with non-traumatic chest pain, does the introduction of a new multimatker strategy compared with the current standard practice of an 8 hour troponin, safely reduce the length of time spent in the emergency department?

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12610000036011

Acronym

REACTED

Enrollment

1000

Registered

2010-01-13

Start date

2009-11-10

Completion date

2010-05-31

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Chest pain is one of the most common reasons for presentation to Australian emergency departments. Despite this little is known about the safety of our current practice, which often involves patients spending many hours in an Emergency department awaiting repeated blood tests and electrocardiograms. Recent introduction of a latest generation super-sensistive troponin to our laboratory combined with an interest in an accelerated 'multimarker stratgey' already in widespread use throughout the UK and the USA (that back in 2006 was ranked as having the same level of evidence as our current practice by the American college of Emergency Physicians) and a desire to increase efficiency we have redesigned the way our department manages patients presenting with non-traumatic chest pain that allows us to confidently discharge patients as soon as 4 hours after the onset of their symptoms. This trial is intended to compare the efficacy and safety of this new process, when compared to the old process.

Interventions

The intervention is the introduction of an accelerated multimarker based chest pain protocol, performing serum Myoglobin, Creatine kinase -MB and Troponin-I on arrival and either 2 hours later or at least 4 hours after the onset of the patients maximal pain, whichever is later

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Diagnosis

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Age >/= 18 Presenting with non-traumatic chest pain

Exclusion criteria

Age <18. Traumatic cause of chest pain

Outcome results