None listed
Conditions
Brief summary
A small number of multidisciplinary lifestyle interventions for diabetes prevention and weight reduction have been conducted in obese Polynesian (Maori and Pacific Islands people) populations but to date none were designed to isolate the specific impact of the exercise component. To our knowledge, no structured exercise trials have been conducted in obese Maori and Pacific Islands people with type 2 diabetes. Therefore, the purpose of this study was two-fold: (1) to evaluate whether high intensity resistance training (weight lifting) or aerobic exercise can improve glycemic control and associated cardiometabolic aberrations in sedentary Polynesian people with morbid obesity and diagnosed type 2 diabetes; and (2) to determine which type of exercise is more effective for improving glycemic control given an equivalent training intensity and duration. Because resistance training has been shown to improve overall muscle strength and metabolism, we hypothesised that this form of exercise would result in greater reductions in glycated haemoglobin
Interventions
16 weeks of progressive resistance training (weight lifting), three times per week, 45 min per session on eight machine-based resistance exercises in a circuit format: seated leg press, knee extension, knee flexion, chest press, lat pulldowns, overhead press, biceps curls, triceps extension (Cybex International, Medway, MA). Initial weights starting weights determined as a percentage of the extrapolated 1-repetition maximum (1RM) as previously described by Brzycki et al (1993). Thereafter usin
16 weeks of progressive resistance training (weight lifting), three times per week, 45 min per session on eight machine-based resistance exercises in a circuit format: seated leg press, knee extension, knee flexion, chest press, lat pulldowns, overhead press, biceps curls, triceps extension (Cybex International, Medway, MA). Initial weights starting weights determined as a percentage of the extrapolated 1-repetition maximum (1RM) as previously described by Brzycki et al (1993). Thereafter using a graduated periodized regimen where subjects progress from 65% to 85% of their extrapolated 1RM over the course of phase 1, two sets at 85% during phase 2, three sets at 85% during phase 3, and a continuation of three sets at 85% until conclusion of the intervention. Perform 6 to 8 repetitions with a 1 minute rest between sets. Workloads increased by 5% when subjects can perform 10 repetitions. Onsite exercise leaders supervised by lead clinical exercise physiologist encourage exercise at a a perceived exertion of “hard,” or 15, on the Borg scale.
Sponsors
Massey University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
Self-identified Polynesian descent (Maori, Pacific Islands people). Diagnosed type 2 diabetes. Central obesity as defined by a waist girth of 88cm in women and 102cm in men. No change in diabetes medications for previous two months. No documented cardiac history or stable cardiac history for previous 6 months. Not currently taking exogenous insulin injections. Must be stable and medically managed. Signed consent from their general practitioner (GP) or specialist.
Exclusion criteria
Diabetic complications which may be worsened by weight lifting exercise. Change in meds during previous 2 months. Unstable cardiovascular disease, stroke, or other conditions which might be worsened by weight lifting exercise.
Outcome results
None listed