None listed
Conditions
Brief summary
Stroke is a leading cause of disability among adults worldwide. Many people who experience stroke have ongoing weakness and clumsiness in one hand and arm. In this study, people at the chronic stage of stroke will have a two week ‘burst’ of physiotherapy for their hand and arm. A non-invasive magnetic stimulation technique will be used before each session to prime the brain for a better response to therapy. Participants will be randomly assigned to have either this priming technique, or a placebo version. Participants in both groups are expected to benefit from the two week ‘burst’ of physiotherapy. This study will find out whether the priming technique will produce any additional benefit. The development of short and effective primed therapy protocols may lead to further functional recovery in people with stroke.
Interventions
Non-invasive transcranial magnetic stimulation will be delivered in a protocol called theta burst stimulation. This protocol involves a 2 second train of low intensity stimuli, repeated every 10 seconds for 192 seconds (600 stimuli in total). This protocol will be delivered prior to an upper limb physiotherapy session, 5 days per week for 2 weeks. Each physiotherapy session will be one-on-one with a registered physiotherapist, last approximately 45 minutes, and will be tailored to the individ
Non-invasive transcranial magnetic stimulation will be delivered in a protocol called theta burst stimulation. This protocol involves a 2 second train of low intensity stimuli, repeated every 10 seconds for 192 seconds (600 stimuli in total). This protocol will be delivered prior to an upper limb physiotherapy session, 5 days per week for 2 weeks. Each physiotherapy session will be one-on-one with a registered physiotherapist, last approximately 45 minutes, and will be tailored to the individual's needs and goals.
Sponsors
University of Auckland
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
One stroke within previous 6 to 36 months Upper limb impairment
Exclusion criteria
Epilepsy Cardiac pacemaker History of more than one stroke
Outcome results
None listed