None listed
Conditions
Interventions
Protocol directed and energy restricted nutritional support during management of refeeding-related hypophosphataemia. Protocol currently under development by management committee and will be based on review of best available evidence.
Sponsors
National Health and Medical Research Council (NHMRC)
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients will be considered eligible for the trial is all of the following inclusion criteria are met at the time of screening: 1)Presence of refeeding hyphosphataemia (a serum phosphate drop of more than 0.16mmol/l from a previous reading to below 0.65mmol/L within 72 hours of the onset of nutritional support, 2)Age at least 18 years, 3) ICU specialist intends to manage the patient with continued normal nutritional support
Exclusion criteria
Patients will be considered ineligible for the trial if any of the following exclusion criteria are met at the time of screening: 1)Intensive Care Unit (ICU) discharge anticipated on day of screening or day after screening, 2)Diabetic ketoacidosis, 3)Presence of acute or chronic renal failure, 4)Admitted to the Intensive Care Unit (ICU) for palliative care only and not expected to survive hospital discharge, 5)Moribund and not expected to survive 24 hours, 6)Brain dead or suspected to be brain dead, or 7)Admitted to the study Intensive Care Unit (ICU) directly from another Intensive Care Unit (ICU).
Outcome results
None listed