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Clinical study of vitreous surgery with direct central retinal artery massage for the treatment of central retinal artery occlusion

In patients with central retinal artery occlusion, is vitreous surgery with direct central retinal artery massage superior to traditional treatment in improving circulation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12609001042235
Enrollment
300
Registered
2009-12-07
Start date
2005-01-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of the study is to evaluate the effect and safty of vitreous surgery with direct central retinal artery massage for central retinal artery occlusion. Pressing the central retinal artery in the optic nerve head with a probe or retrobulbarly with a sclera depressor led to deformation and bending of the blood vessel wall. During the mechanical movement of the vessels induced by the probe, the embolus may be broken into smaller pieces and then be dislodged, followed by curculation recovery. More than 15 cases received the sugical treatment, and more than 100 patients received the traditional treatments.

Interventions

After standard 3 port pars plana vitrectomy(PPV),a probe specialy desinged for the surgery was used to penitrate into the optic nerve head along the central retinal artery, at the same time, diretcly massaging along the central retinal artery wall (5-6 times, about 3 minutes).If the circulation did not recover, then a scleral depressor was used to press the optic nerve slightly retrobulbarly 5-6 times (about 2 minutes).

Sponsors

Beijing Tongren Eye Center
Lead SponsorHospital

Study design

Allocation
Non-randomised trial
Intervention model
Other
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No

Inclusion criteria

tipical central retinal artery occlusion occurred within 4 days

Exclusion criteria

with other eye diseases that affect vision

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026