Randomized prospective trial of cyclosporine with/without low-dose prednisolone in idiopathic membranous nephropathy in adults with nephrotic syndrome

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000996268

Acronym

CYPMEN (CYclosporine with/without Prednisolone in MEmbranous Nephropathy) study

Enrollment

Registered

2006-03-31

Start date

2000-06-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Oral administration of cyclosporine 3 mg/kg/day and prednisolone 15 mg/day, for a total of 24 months

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

16 Years to 80 Years

Healthy volunteers

Inclusion criteria

Biopsy proven idiopathic membranous nephropathy. Over 3.5 g/day of excretion of urinary protein.

Exclusion criteria

Secondary forms of membranous nephropathy. Less than 70 ml/min of creatinine clearance. Patients with relapse or recurrence. Treated with other immunosuppressants.

Outcome results