None listed
Conditions
Brief summary
The aim of this study is to examine the effect of intraperitoneal LA on the requirement for postoperative and pain intensity after long duration of pneumoperitoneum. We also hypothesize that the timing of administration of intraperitoneal local anesthetics(LA) will affect to postoperative pain.
Interventions
There are three groups in total: Group I(infiltration), Group D(Double0, Group C(
Control).
Group I(Infiltration) : infiltration ropivacaine only at the beginning of the surgery
Group D(Double) : infiltration ropivacaine twice during the surgery (time of start and end of surgery)
Immediately after creation of pneumoperitoneum and place of the first two trocars 1 mg/kg of ropivacaine in 100 ml normal saline in Group I and Group D will be sprayed on the upper surface of right and left lobe of liv
There are three groups in total: Group I(infiltration), Group D(Double0, Group C( Control). Group I(Infiltration) : infiltration ropivacaine only at the beginning of the surgery Group D(Double) : infiltration ropivacaine twice during the surgery (time of start and end of surgery) Immediately after creation of pneumoperitoneum and place of the first two trocars 1 mg/kg of ropivacaine in 100 ml normal saline in Group I and Group D will be sprayed on the upper surface of right and left lobe of liver and left hemidiaphragm. At the end of the operation and before withdrawing the first trocar, 100ml normal saline in Group I and 1 mg/kg of ropivacaine in 100 ml normal saline in Group D will be sprayed on the upper surface of right and left lobe of liver and left hemidiaphragm in Group D. This is one off treatment.
Sponsors
Chuna-Ang University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
Patients will be scheduled to undergo elective laparoscopic colectomy.
Exclusion criteria
Patients weigh under 45 kg or over 100 kg, have severe underlying cardiovascular, renal, hepatic diseases, and have allergy to local anesthetics will be excluded.
Outcome results
None listed