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Can lower limb sensory retraining reduce sensory loss after diabetic neuropathy? A randomised controlled pilot study

The effect of sensory neuropathy retraining versus education only on lower limb sensory loss in people aged 40-70 years old with a history of diabetic neuropathy

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12609000931279
Enrollment
30
Registered
2009-10-29
Start date
2009-12-07
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

In summary, diabetes is a major health concern worldwide with its prevalence continuing to increase. Diabetic neuropathy is associated with pain, loss of sensation, loss of ambulation, decreased quality of life and can ultimately result in amputation. Previous studies have shown that central loss of sensation can be decreased with sensory retraining, particularly in people with chronic sensory loss, proving it is more of a “learned” non-use mechanism. Therefore it can be postulated that a sensory retraining intervention for diabetic patients may improve their peripheral sensory appreciation (via attention and practice) which may ultimately lead to improved health and quality of life.

Interventions

The sensory intervention is based on previous work (Hillier and Dunsford 2006, Lynch et al 2007) and incorporates in each training session a hierarchy of tasks starting with general education about sensation, how it can become altered and the functional consequences of poor sensation. The actual training tasks require the person to practice identifying various sensory stimuli applied randomly across the soles of the foot and they provide responses related to the type of stimulus and the location

The sensory intervention is based on previous work (Hillier and Dunsford 2006, Lynch et al 2007) and incorporates in each training session a hierarchy of tasks starting with general education about sensation, how it can become altered and the functional consequences of poor sensation. The actual training tasks require the person to practice identifying various sensory stimuli applied randomly across the soles of the foot and they provide responses related to the type of stimulus and the location of the stimulus. The progression of the hierarchy involves more sensitive stimuli, and finer discrimination, based on their previous scores. Stimuli begin with pressure monofilaments and temperature (warm versus cold) and progresses to combination stimuli eg a cold floor tile versus softer warm sand. There is also a task of discriminating foot positions where the person is required to more and more accurately discern the foot position (when repositioned by the therapist). Each session will last a half an hour and the person will be seated or lying comfortably throughout. There will be total of 10 sessions over the 2 week period.

Sponsors

University of South Australia
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

1. Partial vibratory sensory loss of the lower limb 2. Aged 40-70 years old 3. Able to attend all assessments and interventions 4. Cognitive ability to follow the instructions of the study 5. Give informed consent

Exclusion criteria

1. Complete vibratory sensory loss of the lower limb 2. No vibratory sensory loss of the lower limb 3. Inability to understand or respond to questions and instructions 4. History of sensory deficits from other neurological disorders

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026