None listed
Conditions
Brief summary
Our gut has hundreds of types of “good” and “bad” bacteria in it. Changes to the diet can affect our gut health, the balance of gut bacteria which can lead to downstream changes to bacterial by-products as a result. The aim of this study is to investigate whether a drink containing fruit fibre, a fruit compound or a combination of fruit compounds and fruit fibre have any beneficial effects on the gut. This will be determined by measuring the types of beneficial and commensal bacteria, investigating the frequency of bowel movements and determining by-products of the digestive process that can benefit the gut lining. We will also be carrying out a questionnaire on digestive well being to see how people feel after including these drinks in their normal diet. Further we aim to determine whether there is any difference in the effects of drinks containing these fruit ingredients and drinks without them. It is hypothesised that the product containing the combination of fruit compounds and fruit fibre will improve overall gut health as determined by the above measures.
Interventions
arm 1 - a 300ml polyphenol beverage containing 500mg polyphenols taken in 2 doses in a day for 4 weeks, arm 2- a 300ml fibre beverage containing 7.5g fibre taken in 2 doses in a day for 4 weeks, and arm 3 - a 300ml polyphenol and fibre beverage containing 500mg polyphenols and 7.5g fibre taken in 2 doses in a day for 4 weeks, with a 2 week washout period between each intervention
Sponsors
New Zealand Institute for Plant & Food Research Limited
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
40 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
Body mass index between 18 and 35kg/m2
Exclusion criteria
They must not have a history of drug or alcohol abuse, be pregnant or breastfeeding, have any gut-related problems (except irritable bowel syndrome), diabetes mellitus, vascular disease, a mental illness, hepatitis, a compromised immune status and they must not have or have had cancer. They must not have anaemia, malnutrition from malabsorption, regularly use anti-inflammatory drugs, consume vitamin or mineral supplements, take fermented milk drinks such as Yakult or take fibre supplements such as Metamucil. They also must not be undertaking extreme exercise or suffer from exercise-related diarrhoea.
Outcome results
None listed