None listed
Conditions
Brief summary
Aims of this project: *To investigate if whole body vibration training is effective and well tolerated over the short-to medium-term. *Medium-term home based training program will evaluate if whole body vibration training influences:- mobility, muscle power and force, muscle mass & bone mass. The hypothesis:- *Is that over a six month period the aims of effectivness and tolerance can be noted in children with Osteogenesis Imperfecta.
Interventions
Both child and parent/carer who are randomised into the vibration arm of the study, will be instructed by the treating physiotherapist to use the Juvent vibration plate. They will be asked to undertake a 12 months program, to stand on the plate for 20 minutes daily.
Frequency is at a low-level (30Hz) as these forces are less than the skeleton experiences through normal ambulation,as such unlikely to result in adverse skeletal events.
Sponsors
Surgical Synergies Pty Ltd
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
2 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
Diagnosis of Osteogeneis Imperfecta (Type l -Vll) To be able to stand on the vibration paltform for a 20 minute period Able and willing to particpate with parent/legal guardian written consent.
Exclusion criteria
Current pregnancy Lower limb fracture within 8 weeks of enrollment Untreated Rickets within 6 months of enrollment Serum 25(OH)2 Vitamin D <39nmol/l History of clinically significant organic or psychiatric disease. History of using medications such as, anabolic agents, calcitriol, calcitonin, fluoride, oestrogen, progestogens, growth hormone, Parathyroid hormone (PTH) Osteoporosis secondary to diseases other than Osteogenesis Imperfecta (OI) Osteoporosis secondary to drug therapies. Current use of anticonvulsant medication Current use of anticoagulant medication
Outcome results
None listed