Cognitive Changes With Adjuvant Therapy For Breast Cancer: A Longitudinal Study

Longitudinal study assessing changes in cognitive function induced by adjuvant therapy in women with early stage breast cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12609000893202

Enrollment

200

Registered

2009-10-13

Start date

2003-11-20

Completion date

2010-09-23

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Patients receiving adjuvant treatment with chemotherapy commonly complain of impaired mental functioning during and after treatment. This study evaluates changes in various aspects of mental function starting before any adjuvant treatment and at various time points up to 2 years later.

Interventions

No intervention related to the trial - only observation of changes in cognitive function induced by adjuvant therapy over the first two years from initiation of treatment (the choice of which is not influenced by participation in this study).

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1.Women diagnosed with early breast cancer treated by surgery with curative intent 2. Adjuvant therapy is planned (chemotherapy, hormone therapy, radiotherapy, or any combination of the above) 3. Fluency in English

Exclusion criteria

1. Current use of hormone replacement therapy or hormonal contraception 2. Severe current mental illness 3. Not able to comply with the test requirements 4. Pre-existing significant neurological impairment

Outcome results