Comparison of Intraoperative Safety and Postoperative Lung Complications between two ventilation methods during lung resection surgery

Comparison of Intraoperative Safety and Postoperative Lung Complications between Conventional and Protective One Lung Ventilation Strategies in Lung Resection Surgery

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000861257

Enrollment

120

Registered

2009-10-06

Start date

2009-05-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Purpose: Comparison of postoperative lung complications between two ventilation methods in lung resection surgery. Hypothesis: ventilation with low tidal volume and oxygen partial pressure, application of positive endexpiratory pressure, and pressrue controlled ventilation will reduce postoperative lung complications compared to conventional ventilation methods

Interventions

The protective ventilation strategy consists of fraction of inspired oxygen (FiO2) 0.5, tidal volume 6 ml//kg, end expiratory pressure 5 cmH2O, and pressure controlled ventilation./protective ventilation strategy applied during one lung ventilation (approximately 60 minutes)

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

20 Years to 80 Years

Healthy volunteers

Inclusion criteria

1. Lung resction surgery: lobectomy, bilobectomy. 2. American society of anesthesiology physical status 1 or 2 3. Patients acceptance for the study

Exclusion criteria

1. patient’s refusal 2. cerebral, renal or liver diseases

Outcome results