Observational study assessing the laryngeal and pharyngeal spread of topical local anaesthetic administered orally during general anaesthesia in children

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12609000842268

Acronym

Topical anaesthesia of the paediatric airway (TAPA)

Enrollment

120

Registered

2009-09-29

Start date

2008-02-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study has been designed to determine the effectiveness of a routine anaesthetic practice at the Royal Children's Hospital (RCH) in Melbourne. At this institution, we pour local anaesthetic into the pharynx (throat) of children having general anaesthesia with a tracheal tube (breathing tube) in the hope that the larynx will become partially anaesthetised in order to reduce adverse events during anaesthesia such as coughing, laryngospasm (the vocal cords clamping together), oxygen levels dropping in the patient's blood, or slowing of heart rate.

Interventions

Observational study to assess the spread of local anaesthetic solution throughout the pharynx and larynx. Children having a general anaesthetic requiring a tracheal tube will have local anaesthetic poured into the back of the mouth. The local anaesthetic will be stained with methylene blue dye, so that the investigator is able to determine which parts of the patient have come into contact with the local anaesthetic. The study is expected to be completed within two years.

Eligibility

Sex/Gender

All

Age

6 Months to 16 Years

Healthy volunteers

Inclusion criteria

Healthy children undergoing elective surgery requiring tracheal intubation

Exclusion criteria

American Society of Anesthesiologists (ASA) grade 3 and above (patients with significant medical problems)

Outcome results