None listed
Conditions
Brief summary
Studies in animals with retinal dystrophies shows benefit from light restriciton. In particular improvement in retinal function as measured by an elecroretinogram. This study is being undertaken to see if restricting light exposure in people with retinal dystrophies improves retinal function.
Interventions
1 They will be asked to wear an occluding lens (This is an eye patch that fits over the wearers glasses or sticks to the skin if the participant doesn't wear glasses these are the same as what children who have amblyopia "lazy eye" wear) on one eye for up to 12 weeks.
1a. The patch is worn full time during waking hours. There are two exceptions firstly for bathing/ showering and secondly for driving a car. The total time the patch is off should be less than 1 hour.
Sponsors
Dr John Grigg
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
1.Subjects will have a diagnosis of retinal degeneration, with the following admission criteria: Rod-cone dystrophy, non-syndromic Age 18-35 Flash Electroretinogram (ERG) still detectable Dark-adapted thresholds at least 20% of normal
Exclusion criteria
Free of significant other ophthalmic pathology (eg cataract macular oedema or glaucoma)
Outcome results
None listed