None listed
Conditions
Brief summary
This study looks if supervised physical exercise is useful in reducing side effects of hormonal therapy for prostate cancer. Who is it for? You can join this study if you have been enrolled in the Randomised Androgen Deprivation and Radiotherapy (RADAR) study. Trial details: Participants will be divided into two groups. One group will undertake supervised resistance and aerobic exercise. Sessions are 60 minutes each, twice weekly over 6 months. The other group will be provided with a printed booklet with general information about physical exercise. The study will measure aerobic capacity, abdominal obesity, lipid and glycemic control, muscle function and other indicators of well-being before, immediately after the program and 6 months after the program. The use of androgen deprivation therapy (ADT) is accompanied by a number of side effects. This study will investigate the effects of supervised physical exercise on reversing ADT related side effects.
Interventions
Exercise: progressive supervised aerobic (e.g. walking and cycling) and resistance exercises (e.g. upper and lower body resistance based exercise using weight machines) twice weekly (60 minute sessions) for 6 months. The training will be supplemented with a printed booklet containing general information about physical activity.
Sponsors
Edith Cowan University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
Male
Age
0 to No maximum
Healthy volunteers
No
Inclusion criteria
Participants enrolled in the existent Randomised Androgen Deprivation and Radiotherapy trial (RADAR study) (ACTRN12607000097448) from the sites of Perth, Newcastle (Australia) and Wellington (New Zealand).
Exclusion criteria
1) metastatic bone disease; and 2) presence of muscoloskeletal, neurological or cardiovascular disorders that may inhibit participants from exercising.
Outcome results
None listed