None listed
Conditions
Brief summary
The primary purpose of this study is to evaluate the effectiveness of adding nasal saline spray to usual care in reducing the symptoms of the common cold and acute rhinosinusitis. It is expected that using nasal saline spray will reduce the severity and duration of symptoms.
Interventions
Nasal saline spray administered at least 4 times per day in addition to usual care (excluding other nasal decongestants) until resolution of symptoms (considered the first day they are no longer troublesome and participants answer "yes" to the question "Are you well again?") or for 6 weeks, whichever comes first.
Sponsors
Dr Deborah Askew
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
2 Years to No maximum
Healthy volunteers
No
Inclusion criteria
patients >= 2 years of age presenting to a participating General Practitioner (GP) with common cold with symptoms of runny nose, sore throat, sneezing, cough, lethargy etc, or acute rhinosinusitus. For inclusion, participants must have had symptoms for =5 days and =3 weeks.
Exclusion criteria
Patients will not be eligible if they have known or suspected Chronic Obstructive Pulmonary Disease (COPD); have been, or wish to use steam inhalations; have anatomical abnormalities or physical impairment preventing compliance with study protocol; have cognitive impairment preventing informed consent; or are known to the GP as having other social or medical issues that preclude involvement in this study. Any patient who, subsequent to the recruitment consultation, receives a positive identification of pertussis infection (Whooping Cough) will be excluded from the study.
Outcome results
None listed