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Dysphagia in Inflammatory Muscle Diseases: Answering the Questions Who, Where, Why and What to Do?

Dysphagia in Inflammatory Muscle Diseases: Answering the Questions Who, Where, Why and What to Do?

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12609000671268
Enrollment
70
Registered
2009-08-06
Start date
2009-08-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aims to better investigate the underlying problem behind the swallowing difficulties (dysphagia) experienced by many people diagnosed with inflammatory muscle disorders (Inclusion Body Myositis, Dermatomyositis and Polymyositis)

Interventions

using videofluoroscopy and manometry to investigate the mechanisms behind swallowing problems reported by patients with inflammatory muscle diseases Videofluoroscopy is a procedure where patients ingest radioopaque barium sulphaate mixed with small amounts of food/fluids. The procedure is x-rayed using a fluoroscope and recorded to allow frame-by-frame analysis of the swallowing dynamic. The procedure exposes patients to small amounts of ionising radiation (calculated as 0.2 milliseiverts).

using videofluoroscopy and manometry to investigate the mechanisms behind swallowing problems reported by patients with inflammatory muscle diseases Videofluoroscopy is a procedure where patients ingest radioopaque barium sulphaate mixed with small amounts of food/fluids. The procedure is x-rayed using a fluoroscope and recorded to allow frame-by-frame analysis of the swallowing dynamic. The procedure exposes patients to small amounts of ionising radiation (calculated as 0.2 milliseiverts). The Videofluoroscopy will be performed simulataneously with a manometric examination of the swallow. Participants have a purpose built manometric catheter (outside diameter 2.0 mm) inserted via the nares and positioned in the upper oesophageal sphincter. Recordings of upper oesophageal sphincter, oesophageal and pharyngeal pressures will be recorded. TOTAL time for both procedures =30 minutes approx.

Sponsors

Sir Charles Gairdner Hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

diagnosed with inflammatory muscle diseases able to provide informed consent no surgical interventions to head/neck

Exclusion criteria

unable to provide consent surgical intervention to head/neck any other neurological condition

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026