None listed
Conditions
Brief summary
The intent of the study is to determine the accuracy of currently accepted methods of measurement of degree of liver cirrhosis and portal hypertension. This would primarily benefit patients indirectly and may lead to improvement in the techniques used to measure the severity of liver cirrhosis in the future.
Interventions
Measurement of wedged hepatic vein pressure. This involves wedging a balloon catheter in a hepatic vein branch and measuring the pressure. This is done immediately prior to the formation of the Transjugular Intrahepatic Portosystemic Shunt. When the portal vein is accessed by the shunt, the direct portal vein pressure is measured. This will be compared to the initial hepatic vein wedge pressure measurements for the purpose of teh study. These measurements will add approximately 5 minutes to the
Measurement of wedged hepatic vein pressure. This involves wedging a balloon catheter in a hepatic vein branch and measuring the pressure. This is done immediately prior to the formation of the Transjugular Intrahepatic Portosystemic Shunt. When the portal vein is accessed by the shunt, the direct portal vein pressure is measured. This will be compared to the initial hepatic vein wedge pressure measurements for the purpose of teh study. These measurements will add approximately 5 minutes to the scheduled procedure (which takes approximately 40 minutes in total)
Sponsors
Richard Waugh
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Diagnosis
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Age above 18 years Patient undergoing formation or revision of Transjugular Intrahepatic POrtosystemic Shunt Able to give informed consent
Exclusion criteria
Age under 18 years
Outcome results
None listed