Increasing appropriate screening for colorectal cancer patients and their first degree relatives. A randomised controlled trial.

Conditions

None listed

Brief summary

This research aims to improve adherence to guideline recommendations for surveillance for people with colorectal cancer and screening of their first degree relatives using an educational intervention. People with colorectal cancer and their first degree relatives will be randomly assigned to receive tailored educational materials on screeening (intervention group) or standard pamphlets (minimal ethical care group). It is expected that those in the intervention group will have 10%, 12% and 15% higher levels of adherence to screening/surveillance recommendations at 1, 2, and 3 years post recruitment respectively, when compared with those in the minimal ethical care group.

Carey M, Sanson-Fisher R, Macrae F, Cameron E, Hill D, D'Este C, Doran C.

2017-02-065 citations

10.1186/s12885-017-3095-x

A randomized controlled trial of the effectiveness of a pre-recruitment primer letter to increase participation in a study of colorectal screening and surveillance

Christine Paul, Ryan J. Courtney, Rob Sanson‐Fisher, Mariko Carey, David Hill et al. (7 authors)

BMC Medical Research Methodology2014-04-0110 citations

10.1186/1471-2288-14-44

A population-based cross-sectional study of colorectal cancer screening practices of first-degree relatives of colorectal cancer patients.

Courtney RJ, Paul CL, Carey ML, Sanson-Fisher RW, Macrae FA, D'Este C, Hill D, Barker D, Simmons J.

2013-01-1041 citations

10.1186/1471-2407-13-13

Improving adherence to surveillance and screening recommendations for people with colorectal cancer and their first degree relatives: a randomized controlled trial.

Carey M, Sanson-Fisher R, Macrae F, Hill D, D'Este C, Paul C, Doran C.

2012-02-0814 citations

10.1186/1471-2407-12-62

Interventions

People with bowel cancer and their first degree relatives will be allocated to an intervention or minimal ethical care group. Those in the intervention group will be posted a detailed information booklet about screening tests recommended by the National Health and Medical Research Council (NHMRC). A corresponding information booklet will also be mailed to their General Practitioner (GP) and for index cases only, cancer surgeon. This tailored advice on screening will be provided to participants

People with bowel cancer and their first degree relatives will be allocated to an intervention or minimal ethical care group. Those in the intervention group will be posted a detailed information booklet about screening tests recommended by the National Health and Medical Research Council (NHMRC). A corresponding information booklet will also be mailed to their General Practitioner (GP) and for index cases only, cancer surgeon. This tailored advice on screening will be provided to participants and their clinicians within 4 weeks of recruitment, and 12 and 24 months later.

Study design

Allocation

Randomised controlled trial

Primary purpose

Prevention

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

Index Cases - People who have received a confirmed diagnosis of bowel cancer no more than 6 months previously. First degree relatives - Of people with bowel cancer particpating in the trial.

Exclusion criteria

Index cases - People with familial adenomatous polyposis or hereditary non-polyposis colorectal cancer (HNPCC). Non-English speaking. First-degree Relatives - Those with familial adenomatous polyposis or hereditary non-polyposis colorectal cancer (HNPCC), ulcerative colitis, Crohn’s disease, inflammatory bowel disease or a previous diagnosis of bowel cancer. Non-English speaking.

Outcome results