Pilot study of the effects of low salt intake on obstructive sleep apnoea

In moderate-severe untreated obstructive sleep apnoea (OSA) patients who have a high sodium intake, does a 7-day low-sodium diet reduce apnoea-hypopnoea index

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000624280

Enrollment

Registered

2009-07-27

Start date

2009-10-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary purpose of this study is to find out if high salt intake contributes to the severity of obstructive sleep apnoea. Our hypothesis is that reduction of salt intake in people with moderate to severe sleep apnoea will reduce the symptoms of the sleep apnoea.

Interventions

Low sodium diet (< 50 mmol/day) for 7 days

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

Male

Age

20 Years to 60 Years

Healthy volunteers

Inclusion criteria

Apnoea-hypopnoea index >=15 20 < Body mass index (BMI) < 30 kg/m2. Baseline 24 hour urine sodium excretion >= 200 mmol/day.

Exclusion criteria

Continuous Positive Airway Pressure (CPAP) or other treatment for OSA. Anatomical features known to cause OSA. Office Blood Pressure (BP) < 100/60 mm Hg at baseline. Current treatment for hypertension. Diabetes. Pathology that might cause fluid retention

Outcome results