None listed
Conditions
Brief summary
Our current practice at the Launceston General Hospital (LGH) and many centres in Australia is to administer platelets via a free flowing gravity line. However there are a few reports that employ a pump during platelet-administration as an acceptable practice. Administration of platelets via a pump would ensure the platelets are infused in a timely fashion but in the meantime, we should ensure that the pumping action will not damage the platelets. There are 2 pumps currently available on the oncology ward at the LGH and used for red cell transfusion; the Graseby 3000 and the Imed Gemini PC-1 and PC-2 (double pump). Furthermore the pump offers wellcontrolled infusion rate, accurate volume measurement and an alarm system for monitoring infusion. There is very little data, if any, comparing the effect of the above two recognised methods on platelet-increment after transfusion. This pilot study is aiming to determine whether infusion method influences the quality and quantity of platelets transfused. Also to determine the most efficient procedure for the administration of platelets.
Interventions
Our current practice at the Launceston General Hospital (LGH) and many other medical centres in Australia is to administer platelets via a free flowing gravity line. However there are a few reports that employ a pump during platelet-administration as an acceptable practice. Administration of platelets via a pump would ensure the platelets are infused in a timely fashion but in the meantime, we should ensure that the pumping action will not damage the platelets. There are 4 methods for platelets
Our current practice at the Launceston General Hospital (LGH) and many other medical centres in Australia is to administer platelets via a free flowing gravity line. However there are a few reports that employ a pump during platelet-administration as an acceptable practice. Administration of platelets via a pump would ensure the platelets are infused in a timely fashion but in the meantime, we should ensure that the pumping action will not damage the platelets. There are 4 methods for platelets transfusion including 3 pumps currently available on the oncology ward at the LGH and used for red cell transfusion; 1. The Graseby 3000 2. the Imed Gemini PC-1 and PC-2 (double pump) and 3. Baxter Pump. Furthermore the pump offers well controlled infusion rate, accurate volume measurement and an alarm system for monitoring infusion. 1. gravity flow method - platelets transfused over approximately 30 minutes; 2. Transfusion using the Graseby 3000 takes approximately 15-20 minutes; 3. Transfusion using the Imed Gemini PC-1 and PC-2 (double pump) takes approximately 20 minutes. 4.Transfusion using the baxter pump takes approximately 20 minutes There is very little data, if any, comparing the effect of the above two recognised methods on platelet-increment after transfusion. This pilot study is aiming to determine whether infusion method influences the quality and quantity of platelets transfused. Also to determine the most efficient procedure for the administration of platelets either via electromechanical pump or through gravity method. The study will take place until end of Dec 2009.
Sponsors
Clifford Craig Medical Trust Foundation
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients requiring a platelet infusion.
Exclusion criteria
1. Patients with severe infection/ sepsis with temperature>38.5 C. 2. Patients with coagulopathy / DIC 3. Patients with platelet refractoriness e.g. platelet antibody or human leucocyte antigen (HLA) antibody. 4. Patients under the age of 18 years. 5. Patients with an intellectual or mental impairment.
Outcome results
None listed