Maternal Sleep Health and Foetal Outcomes

The relationship between maternal sleep health and foetal growth restriction and cardiotocography (CTG) in pregnant women at risk of sleep-disordered breathing versus healthy pregnant women.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12609000587202

Enrollment

Registered

2009-07-15

Start date

2009-10-15

Completion date

2011-07-21

Last updated

2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The study will investigate the association between sleep-disordered breathing during pregnancy and foetal growth and well-being. It is hypothesised that Obstructive Sleep Apnoea is detrimental to foetal health (acute foetal compromise as evidenced by abnormal cardiotocography (foetal heart rate monitoring) during sleep and impaired foetal growth in late pregnancy).

Interventions

Foetal growth will be observed via ultrasound at 32 and 36 weeks gestation, and at birth. Sleep and foetal heart rate will be monitored with polysomnography and cardiotocography at 38 weeks gestation, for one 8 hour overnight session.

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Yes

Inclusion criteria

between 20-24 weeks gestation Risk factors for sleep disordered breathing, including pre-pregnant obesity (Body Mass Index (BMI) greater than 30kg/m2) and snoring (cases); healthy controls with no history of snoring.

Exclusion criteria

Multiple pregnancy, current pregnancy complicated by pre-eclampsia, previously diagnosed and treated Obstructive Sleep Apnoea (OSA) or other sleep disorder, e.g. narcolepsy, periodic leg movements in sleep (PLMS).

Outcome results